POOR GOAL-DIRECTED BEHAVIOUR IN PATIENTS WITH SCHIZOPHRENI. Un deficiente comportamiento direccionado hacia una meta en pacientes con esquizofrenia
- Authors
- Zirit Cruz, Daniela
- Format
- MasterThesis
- Status
- publishedVersion
- Description
Goal-directed behaviour depends on two systems: 1) the acquired knowledge of the association between an action and its consequences; and 2) the value given to those consequences (Griffiths, Morris and Balleine 2014; Dolan and Dayan 2013; Balleine and Dickinson, 1998; Dickinson and Balleine. 1994). Poor goal-directed behaviour in schizophrenia may be related to a deficiency in one of the systems or furthermore it may rely in an inability to integrate both systems correctly. The present study tested twenty one healthy adults (HA) with no personal or familial history of psychosis, and 14 people with schizophrenia (SZ) or schizoaffective disorder and no other disorder with age between 26 and 65 years old, using a computerized model of an instrumental learning task. The aim of the study was to determine SZ capacity of learning the reward contingencies of each action (Contingency test), and their ability to learn the causal relationship between the action and outcome (A-O) (Degradation test). The different results obtained between the contingency and degradation tests in SZ suggest a possible impairment in learning A-O associations when random outcomes -an outcome delivered in the absence of its associated action- were included. Furthermore, this impairment of goal-directed behaviour in SZ correlated with self-reported disability (WHODAS) [r = -0.39, p = 0.03].
- Publication Year
- 2015
- Language
- eng
- Topic
- COMPORTAMIENTO
ESQUIZOFRENIA
RELACI?N CAUSAL
ASOCIACI?N ACCI?N-RESULTADO
- Repository
- Repositorio SENESCYT
- Rights
- openAccess
- License